Seminar Organising Committee

Alexandra Moreno Mitchell

I am a PhD student in the Faculty of Health and am working on an interdisciplinary project between the Department of Chemistry and the Division of Clinical Medicine with Dr Tim Craggs and Dr Chris Toseland. My project aims to develop and optimise an assay for early cancer detection using single molecule technology.

Evelyn Smith

In July 2018 I graduated from an integrated MChem in Chemistry with Biological and Medicinal Chemistry from the University of Sheffield. My Masters' project looked at developing a drug screening assay to find protein interaction inhibitors between amyloid-beta oligomers and cellular prion protein for the potential use in Alzheimer's disease. In October 2018 I began studying for a PhD supervised by Dr. Alison Twelvetrees and Dr Tim Craggs, applying single molecule FRET to understand kinesin activation. I successfully completed my PhD in January 2023 and now work as a postdoc.

Georgia Taylor-Vine

I am a student within the Department of Chemistry, working on an interdisciplinary project across the Department of Chemistry and the Division of Clinical Medicine with Dr Tim Craggs, Dr Gareth Richards and Prof Joe Harrity. The aim of my project is to create a new SMALP based drug screening assay for GPCR heterodimers, ultimately focusing on the use of single molecule fluorescence correlation spectroscopy which will be conducted within the Craggs lab.

Katie Gelder

I am a postdoctoral researcher in Dr Dan Bose’s lab within the School of Bioscience, working in collaboration with Dr Ali Twelvetrees from the Sheffield Institute for Translational Neuroscience (SITraN) and Dr Tim Craggs from the Department of Chemistry. My project focuses on the phase separation of CREB binding protein (CBP), and how condensates affect CBP dynamics and activity. My current interests include single molecule imaging and single molecule fluorescence resonance energy transfer (smFRET). Anything that involves blobs and microscopy, count me in!

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